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Pre-Clinical Research

Obtaining high quality of toxicology data in early stages of developing a new drug is critical and highly significant.
For toxicology studies, Pharma Instinct complies with the norms of Good Laboratory Practices (GLP) and performed by suitably qualified and trained persons. We have over two decades of experience of pre-clinical research.

General range of toxicology studies

  • Single dose (acute) toxicology testing
  • Sub-acute toxicology testing
  • Repeat dose (chronic) toxicology testing
  • Sub-chronic toxicology testing

Other studies

  • Proof of concept studies
  • In-vitro experiments
  • Pharmacological mechanism studies

Animal species

  • Rat
  • Mice
  • Rabbit

Drug administration routes

  • Oral
  • Nasal
  • Intradermal
  • Intravenous/Intramuscular/Intraperitoneal

Significance of Preclinical research

The result from preclinical toxicology studies gives following information:

  • Establish a safe starting dose for clinical studies
  • Provide information on a drug-treatment regimen that would produce the least toxicity
  • Assess target organ toxicity & its reversibility
  • Provide insight into biomarkers for clinical monitoring